Tuesday, December 24, 2019

Family and Death - 2650 Words

Loss can be described as many things; the misplacement of tangible items, the ending of a close relationship with a friend, a goal not achieved or the death of a loved one. Through the readings, posts and responses of this course we have seen that individuals each respond to their loss in ways that are unique to them, yet there is a common thread amid it all - everyone grieves and mourns their losses and their lives are forever changed. While reviewing the losses that I have experience, I at first attempted to define which would be the most significant and there for most deserving of further thought and ultimately inclusion in this lossography. What I realized was that significant does not always mean huge or all encompassing, that some†¦show more content†¦I do not mean to diminish the impact the other losses had, certainly seeing the affect my grandfathers death had on my grandmother shaped some of my ideas not only of grief, she was never the same, she did not laugh as mu ch and the light in her eyes was not as bright, but it also shaped some of my ideals about romantic love. To the day she died - 28 years after my grandfather - my grandmother kept all of her checks and official documents titled â€Å"Mrs. Willis Goodrich†, and she never removed her wedding ring. The death of my Uncle Forest was the first time I associated anger with death, my Aunt seemed so numb at first and then for months she was so angry at him for not taking better care of himself, for continuing to smoke when she asked him repeatedly to try to stop and for not asking for help moving the ice house he was pushing when he had a massive heart attack and died. She told me later that it was not until she not only recognized but believed that he had not been trying to die, that he had not wanted to leave her any more than she wanted him to leave, that she was finally able to forgive him for dying and move on with her life. My grandmothers death was different from my grandfather s not only because it was not entirely unexpected, she was almost 90 and had advanced Parkinson’s disease, but more in how I reacted to it.Show MoreRelatedThe Death Of A Family1590 Words   |  7 PagesIn society, talking about death from AIDS occurs rarely, yet bringing attention to the topic will be helpful. The commonality of this disease in the culture makes it almost impossible to avoid its effects. Despite the vast spread of the disease, any person who has contracted the disease will not be able to live a normal life with everyone being aware of their condition. Antiguans considered Jamaica Kincaid’s brother Devon to be an outsider, proven especially by his death and funeral. Her brother sRead MoreThe Death Of A Family845 Words   |  4 PagesDeath is a topic that most people try to avoid, especially the death of a loved one. The spouse or family member may feel awkward and decline discussing the death. However, some are eager to discuss the lost depending on t he stage of the grieving process. This paper will discuss two different interviews that were conducted February 10, 2016, which involved â€Å"church† people who have experienced the physical death of a significant human relationship. My first interviewee was Mr. Thomas a deacon atRead MoreThe Death Of The Family1418 Words   |  6 PagesDeath of the Family America has made great progress on the world stage with her technology. The inventions of the computer, cell phones, and internet have become a crucial part of life for many around the world. With all the technology, America, has been unable to stop the murder of her families. Hundreds of families each day are being murdered by the very technology that was invented to make life better. Not all the murders have been carried out directly by the technology itself. Some families haveRead MoreThe Death Of My Family921 Words   |  4 PagesDeath is one of those touchy subjects that no one likes to talk about. It is hard to talk about something that forces you to acknowledge the fact that your life can end unexpectedly at any point and time. You may be prepared to die, you may not. As a child I was not exposed to death all that much. I remember as a child hearing about family members dying but it did not affect me as much as it did my parents; I was young, I didn’t really know that many people in my family at the time where as my parentsRead MoreDeath Of A Family Member932 Words   |  4 PagesThe article states that mouring and grief are experienced by everyone no matter where one comes from. It also said that mourning is the response to some illness of someone , death of a family member , friend , animal or someone close to an individual .(Axelrod, 1969). Elisabeth stated that bereavement takes a length of time and different steps to overcome all the intensity level of pain. She said, there are five stages of grieves and the stages do not necessarily occur on a specific order to someoneRead More A death in the family Essays2012 Words   |  9 Pages James Agees A Death in the Family is a posthumous novel based on the largely complete manuscript that the author left upon his death in 1955. Agee had been working on the novel for many years, and portions of the work had already appeared in The Partisan Review, The Cambridge Review, The New Yorker, and Harpers Bazaar. Published in 1957, the novel was edited by David McDowell. Several lengthy passages, part of Agees manuscript whose position in the chronology was not identified by the authorRead MoreThe Death Tax and the Death of Family Farms Essay1496 Words   |  6 Pagesthe tax rate will increase to fifty-five percent (Finnerty). Lowering the estate tax exemption while increasing the rate may consequently cause the liquidation of many multigenerational family farms and an ultimate decrease in the world’s food supply. Comprehending the effect of estate taxes on farm families requires a general understanding of farm economics. In Illinois, for example, there are 76,000 farms and more than 28 million acres of farm land. Therefore, the average farm size is 368Read MoreThe News Of Death Of A Family Member886 Words   |  4 Pageswhats now imperfect, instantly changing their whole day in just seconds prior to the news of death. Whether the news of death being about a family member, or being the death of a friends’ family member, the news of the occurrence has a powerful effect. Across the world, there are about 151,600 deaths each day. If you were to take each one of those deceased individuals and assume that at least five family members are mentally affected by the news, it shows that there are a minimum of 758,000 peopleRead MoreDealing with the Death of a Family Member1231 Words   |  5 PagesThe death of a family member can greatly affect the family system as it creates a void that is difficult to adjust to. The family experiences a terrible sense of loss, as well as a fear that they have to carry on with their lives without their loved one (Rotter, 2000). They have a hard time picturing there knew life and moving on without them. With the family system changing it may destroy the relationships that already exists in the family (Bowlby-West, 1983). After the death of a family memberRead MoreDeath of a Salesman - Dysfunctional Family845 Words   |  4 PagesA Dysfunctional Family from Death of a Salesman â€Å"We never told the truth for ten minutes in this house.† This quote is said by Biff Loman himself. Willy Loman is the father of Biff and Happy Loman, and the husband of Linda. The Loman’s are an average working class American family. In the play, The Death of a Salesman, written by Arthur Miller, the Loman’s go through very difficult circumstances throughout the play. These circumstances are not exactly obvious but they are shown throughout

Monday, December 16, 2019

Stem Cell Therapy Essay Free Essays

Sepulveda Bio. Anthro. Tues 6-9 Cell Replacement and Stem Cell Therapy to Treat Neurodegenerative Disease Stem cell therapy is being used to treat neurodegenerative diseases such as amyotrophic lateral sclerosis or ALS, commonly referred to as Lou Gehrig’s disease. We will write a custom essay sample on Stem Cell Therapy Essay or any similar topic only for you Order Now The disease itself, new therapies and treatments, along with a cure are currently being studied by universities and stem cell researchers. ALS is a progressive neurodegenerative disease which attacks the neurons in the brain and spinal cord that control voluntary movement, eventually leading to respiratory failure and death (Kamel et al. 2008). The current course of action for a patient with ALS is physical therapy and, if their budget allows, cell replacement therapy. However there is presently no cure and the patient will eventually have respiratory problems and die from the disease. Adult stem cells (ASCs) and blastocyst or embryonic stem cells (ESCs) are being used to treat amyotrophic lateral sclerosis in cell replacement therapy, yet this only slows the degeneration of their neurons (Goldman, Windrem, 2006). Research for both adult stem cell and blastocyst stem cell technologies are the only practical option in approaching a cure or more effective treatment for ALS. Both of these technologies require stem cells, but are challenging to safely retrieve and utilize through the current treatment methods, which is why it is essential to continue to support and fund this research. Cell replacement therapy is currently the only stem cell treatment of neurodegenerative diseases such as ALS, but researchers are trying to find new ways of treating and possibly curing ALS. Cell augmentation using stem cells could be the future of treatment for ALS but scientists are currently working to increase availability of the needed ESCs and ASCs to treat patients using cell replacement therapy. There are three different ways to harvest the necessary stem cells for neuron replacement: growing ESCs in vitro, harvesting stem cells from the brain or spinal cord of a live donor through biopsy, and harvesting from the brain or spinal cord of a donor post mortem (Sohur et. al. , 2006). The goal of treatment of ALS is to slow and eventually stop cell loss progressing to the point of functional impairment. To accomplish this goal, protecting the remaining neurons as well as replacing and augmenting damaged neurons is important. The ultimate goal, to cure ALS, is to fully restore authentic neuronal circuitry or â€Å"full systems reconstruction† (Ormerod et. al. 2008). Full systems reconstruction would consist of recreating a map of precisely patterned neurons of the correct type using the stem cells to send projections to the appropriate field within the brain. The cure seems virtually impossible with the technology currently available, but recreating neurogenesis may be possible in the future. Adult stem cell harvesting is difficult and costly when retrieving the stem cells needed to treat neurodegenerative diseases from brain matter or spinal fluid. Neurons are very specific cells in the brain and spinal cord and possess a special set of neurotransmitters depending on their function; this poses problems when harvesting ASCs (Zhang et. al. , 2006). The ASCs needed to treat ALS must be able to specialize and replace degenerating neurons affected by the disease. This procedure would not be possible without using stem cells to replace the damaged and degenerating neurons. However a problem associated with ASCs is rejection of foreign cells when transplanting ASCs taken through biopsy from a donor. Although biopsy from the patient receiving treatment is an option, the ASCs required come from the brain or spinal cord and can be very dangerous to harvest this way. Adult neural stem cells can be harvested from brain tissue, either from a deceased donor or through biopsy, and then grown in a culture (Ormerod et. al. , 2008). ASCs will not expand nearly as much as ESCs in culture and will differentiate into a limited number of neuron types. When using ESCs, which conform to the necessary specialized type of neurons, the lack of flexibility encountered in the ASCs is eliminated. Human embryonic stem cells (ESCs), however difficult to harvest initially, will multiply greatly when grown in culture. The ESCs are generated by in vitro fertilization and grown into the blastocyst stage before harvesting. The advantages of ESCs are boundless; the results of the therapy would not be obtainable without use of the stem cells to replace the damaged cells. The ease and frequency with which ESCs can be expanded in culture is a significant advantage over ASCs. Growing such high numbers of stem cells in this fashion can prove problematic though, while the cells reproduce indefinitely they become more susceptible to mutation and may cause tumors following transplant (Ormerod et. al. , 2008). Thus, a challenge rises to differentiate the cells fully before transplant or to grow many more cultures from different donor eggs, which are difficult and expensive to receive. ESCs are more easily specialized into neurons, oligodendrocytes, and glia needed to treat ALS than ASCs; but the possibility of tumors forming in the patient along with the cost and complication of creating new chains of blastocysts from donor eggs pose a disadvantage of using this technology (Ormerod et. al. , 2008). Taking into consideration ESC technology’s advantages and disadvantages, it is equally as viable an approach to a cure for ALS as ASC technology. ALS is an extremely destructive disease which unfortunately plagues a large population. ALS is difficult to treat because it is a neurodegenerative disease and requires brain surgery and neuron replacement. Both adult stem cell and embryonic stem cell therapies have potential to increase the quality of life for patients with ALS but they both have their own individual inherent risk that must be taken into account by the patient and doctors when choosing a stem cell therapy method. Donors are few and far between and the necessary cells are very specific for this particular procedure. Through an increase in research and development of new ways to multiply and store stem cells, along with an increase in donors, the road toward a cure will be a short one. Hopefully in the future the treatment will become easier, less costly, and less dangerous for the patient. Works Cited Larsen CS. 2010. Essentials of Physical Anthropology: Discovering Our Origins. New York and London: W. W. Norton Company Ormerod, B. K. , Palmer, T. D. , Maeve, A. C. (2008). Neurodegeneration and cell replacement. Philosophical Transactions: Biological , 363(1489), 153-170. Retrieved from http://www. jstor. org/stable/20210044 Sohur, U. S. , Emsley, J. G. , Mitchell, B. D. , Macklis, J. D. (2006). Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells. Philosophical Transactions: Biological Sciences, 361(1473), 1477-1497. Retrieved from http://www. jstor. org/stable/20209745 Kamel,, F. , Umbach, D. M. , Stallone, L. , Richards, M. , Hu, H. , Sandler, D. P. (2008). Association of lead exposure with survival in amyotrophic lateral sclerosis. Evironmental Health Perspectives, 116(7), 943-947. Retrieved from http://www. jstor. org/stable/25071103 Goldman, S. A. , Windrem, M. S. (2006). Cell replacement therapy in neurological disease. Philosophical Transactions: Biological Sciences, 361(1473), 1463-1475. Retrieved from http://www. jstor. org/stable/20209744 Zhang, S. , Li, X. , Johnson, A. , Pankratz, M. T. (2006). Human embryonic stem cells for brain repair?. Philosophical Transactions: Biological Sciences, 363(1489), 87-99. Retrieved from http://www. jstor. org/stable/20210040 How to cite Stem Cell Therapy Essay, Essays

Sunday, December 8, 2019

Case Study on Strategic Management

Question: Case study on Strategic Management. Answer: 1. Joint Venture how to stop it from being the competitor The company needs to set goals and patters for the companies. These goals need to be one for both the company. They need to understand the profit that they can achieve through joint ventures. They need to merge their culture and develop ways for the development as a team rather than individual (Hill et al., 2014). 2. What entry mode the companies use 2.1. Advantages of Joint venture Access to local partners knowledge- Joint venture helps to access the new market with its customer base. It also enables to gather knowledge on technology, capital and knowledge of the local market. Shared development costs and risk- Joint ventures helps in growth and without borrow funds or looking for the outside investors. Political dependency- It enables to operate when property risk is high as the contracts helps to control and monitor the unforeseen risk in local business (Eden Ackermann, 2013). 2.2 Disadvantages of Joint venture Inability to engage in global strategic coordination- The Company cannot focus on cost reduction which comes from the scale economics and the location economics. Inability to realize location and experience-curve economies- Lack of control over technology- It initiates a handling of technology gap between the two companies (Eden Ackermann, 2013). 3. Explain he risk associated with joint venture dealing with contender strategy Contender Strategy aims to unguarded the niche segments and then upscales it. Contender Strategy in joint ventures enables to lack in quality and the productivity. It also acts as a risk in the service, packaging and delivery. The cost advantage that the country gets in contender strategy would undermine by the deficiencies in the area discussed (Eden Ackermann, 2013). 4. What are the risks of acquisition? Also make recommendation The greatest risk associated with acquisition is the poor and the inadequate communication. It creates complication on the communication strategy and the involvement of the department into it. The mergers need to make proper strategy and communication of all groups need to be there. Secondly, lack of transparency can affect among the stakeholders especially to the employees. All the plans need to be clear to the stakeholders. The mergers and acquisition can lead to mismatch between the plan on the branding, marketing and the sales activities. Again the recommendation regarding this is to make proper set of goals and plans about the marketing and distribution channels. The two companies have two different culture and service standards. So, it becomes tough for the stakeholders and the customers to adopt with the difference. The companies need to understand the culture and for that they need to take time and involve the employees among the companies (Hill et al., 2014). 5. Do they stay as retails or do other activities The Vermont Teddy Bear Company dos not only stay in the retail. It has also involved in many activities. The company does not only retail but it sells it products through their own websites. IT uses various print media like magazines along with story book for children and television shows. The main sales come from the radio. The company is presently in the box of Dog in the BCG Matrix. As the company showing low growth rate with relatively low market share (Eden Ackermann, 2013). 6. Control System 6.1 Balance Scorecard It is the performance matrix used to improve the internal functions of the business and resulting in external outcomes. It helps to turn the organizations mission statement into its strategy (Eden Ackermann, 2013). 6.2 BCG Matrix The framework adopts that with increase in the market share the generation of cash will increase. The four categories are: Dogs- It accounts that low growth arte with the low market share. Question mark- It includes High market growth with the low market share. Stars- It shows High market growth with high market share. Cash Cows- it shows low market growth with high market share. How the company might move from dodger to contender strategy and why this is a risk The dodger strategy focus only on the link in the value chain which require only the local advantage. While the contender strategy concentrates on the gain of the capabilities top became the contender through global recognition. The organization need to confirm that competitive Products are transferable to the overseas and the industry is facing high pressure to globalize. Risk is that company can get strong competition from local competitors. Further it creates risk of financial loss (Hill et al., 2014). 8. Where should the place of the factory The factory needs to be China.. The company needs to expand the market through distribution and export. They can sale their product through their online websites. China has the market with most effective technologies with low structure cost (Eden Ackermann, 2013). 9. What are the strongest forces (Porters factors) and why 9.1 Advantages Competitive Rivalry- Rivalries acts as a threat as the company has plentiful competitors. However the company has advantage over its competitors. It has the label of product manufacturing in USA. So, the materials use is from America which acts as an advantage over its competitors of other countries. The company can deliver the product within overnight. Bargaining Power of suppliers- the company has a strong supplier base in America. The company has numerous options to supplies its products. It has its own websites to sell the products. Bargaining power of customers- The company target customers with age of 1- 100. It enables diverse mediums to attract the customers. Diverse products are available like outfits and jewelry of Teddy bear. It produces the teddy bear with high quality and minimal cost. 9.2 Disadvantage Threats of new entrants- Vermont Teddy Bear have a fear of new entrant in the market of America. The competitive advantage lies mostly in its using the label of USA along with the products of America. Threats of Substitute products and Services- the company target segments are mainly on giving products on gifts and occasions. Now, the company has a threat that the customers can easily move from teddy bear segment to other gift item segments if something new or innovative comes in market. 10. Advantages and Disadvantages of Vertical integration and outsourcing 10.1 Advantages of Vertical Integration It reduce the transportation cost if common ownerships outcome in nearer geograophic possession. Improve coordination of supply chain. Capture the upstream and the downstream margin on profit. Lead expansion on its competencies. 10.2 Disadvantages of Vertical Integration Capacity of balance issue High cost because of low efficiencies because of lack of competition among suppliers. Development of new competencies can affect the existing ones. Increase of bureaucratic cost. 10.3 Advantages of outsourcing Expertise cans compel in faster way giving quality output. Concentrate on core process rather than the supporting one. Outcome of it enables risk-analysis. Reduction in operation and recruitment cost. 10.4 Disadvantages of outsourcing Risk of expose the confidential data. Problem with synchronizing the deliverables. Involvement of hidden cost Lack of customer focus. Vermont Teddy Bear need to develop the outsourcing business process between the two. It would enable them to expand the business through providing expert labor. Moreover they can avail cheap labor without compromising the labor. Outsourcing would enable the company to concentrate on the other crucial business process. They would get expertise with efficiency in technical ability. 11. Cost low profit margins leave risk of low cash flow with profit being primary goal then low cost strategies may be disastrous 11.1 Advantages of low cost structure in industry Economics of Scale- the company can increase its scale of operations in internal growth through organization growth. It initiates external growth through merging and acquiring with other firms. Unique access to low cost input- The organization can get the inputs in much lower cost. It will enable to stimulate its demand through the gain of market share. Learning curve- It enables to provide greater amount of output generation by each labor. It enables to improve the labor skills through job experience. Experience Curve- It enables to initiate a competitive advantage over cost of the reveals. It makes difficult for the new entrant to challenge the existing firm (Hill et al., 2014). 11.2 Disadvantages Coming second, third etc- the company with the involvement of high cost can initiates better operation in management. It makes the company to go far in the competition for its low cost strategy. Technological Progress- the company cannot hire for implement technologically progress materials. It makes the company to adopt further developed ways of costly technologies. Cost reduction focus can cause loss of valued aspects- It will enable the organization to curtail all the necessary adoption. It will enable the profit to gets down. Competitor imitation- the competitors and even the new entrants can easily replicate the process and strategy that company use. 12. International strategy -transnational, international, globalised or standard Are they following this type of strategy, if so in what way and what are the advantages disadvantages 12.1 Advantages It helps Vermont Teddy Bear Company to increase the sales. It helps to increase the visibility. It reduces the operational risk. 12.2 Disadvantage Fragment distribution network in America. Different needs and preferences of customers The Issues in relation with emerge of economics. Vermont Teddy Bear Company concentrates mostly to its American market because of low financial resources. Among the four types in global strategies, company used to follow the international strategy. They mostly concentrate on its domestic market and makes strategies according to it. However to gain the competitive advantage the company adopted the international strategy. 13. Whether organization should diversify or standardize 13.1 Advantages Diversification helps in risk reduction Control the inputs which help to lead community and improve the quality. Control the market through the promising sales and the distribution. Increase in the market share through the introduction of the products in the new customers and market. 13.2 Disadvantages Slow growth in core business. Addition in the management cost. It can cause the bureaucratic complexity. It can reduce to quality as company has to focus on quantity than on quality. Vermont Teddy Bear Company needs to diversify its product in the international market. The company has competitors like Stelff and Glund dwelling mostly in the foreign countries. Vermont Teddy Bear Company has the advantage of using the materials of United States. They can gather the market internationally through selling the product in their own online websites. 14. Diversification and Standardization Diversification is the expansion in the foreign market while standardization refers to the consistency in the same market. The company which are in the initial stage is better to opt for standardization,. But, Vermont Teddy Bear Company has completive advantage in terms of price product place and promotion. Now they need to focus on the expansion in the international market (Hill et al., 2014). 15. Harvest or diverse A harvest strategy is invested when the business is cash cow. It shows that business need to be matured and will grow if more investment added. However, the inclusion of the diverse strategy would lead to increase the people of different culture who want work for growth. Vermont Teddy Bear Company needs to adopt policy on harvest staetegy as it is a mature firm and can grow if invest more (Eden Ackermann, 2013). 16. Reference List Eden, C., Ackermann, F. (2013).Making strategy: The journey of strategic management. Sage. Hill, C., Jones, G., Schilling, M. (2014).Strategic management: theory: an integrated approach. Cengage Learning.